Journal of Multiple Sclerosis and Neuroimmunology 12(1):15-18, 2021
Recurrent Hypertrophic Pachymeningitis Presenting with Various Clinical Manifestations
Min Ji Song, MD, Jeong Hwa Rho, MD, Hyun-Wook Nam, MD, Joo Hye Sung, MD, Seol-Hee Baek, MD
Department of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea
Hypertrophic pachymeningitis (HP) is a rare inflammatory disorder causing localized or diffuse
thickening of the dura mater. It is posited that HP is associated with chronic inflammation.
However, the exact pathophysiology of HP is not known. HP has diverse clinical manifestations
including headache, cranial neuropathies, cerebellar ataxia, and seizure. Here, we report a case
with recurrent HP presenting with diverse clinical manifestations at each attack.
Journal of Multiple Sclerosis and Neuroimmunology 12(1):15-18, 2021