Journal of Multiple Sclerosis and Neuroimmunology 11(2):65-67, 2020
Isolated Optic Neuritis with Diminishing Color Vision as a Spectrum of Bing-Neel Syndrome
Dayoung Kim, MD, Soo Jeong Kim, MDa , Wook Youn Kim, MD, PhDb , Hyun Jin Shin, MD, PhDc , Jeeyoung Oh, MD, PhD
Department of Neurology, Konkuk University Medical Center, Seoul, Korea Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Koreaa Departements of Pathology,b Ophthalmology,c Konkuk University Medical Center, Seoul, Korea
In patients with Waldenström’s macroglobulinemia, various symptoms resulting from
penetration of lymphoplasmacytic lymphoma into the central nervous system (CNS) are called
Bing-Neel syndrome (BNS). Typical neurological symptoms are related with diffuse CNS
involvement, and focal cranial neuropathy is rare in BNS. Here we introduce a patient who
showed dyschromatopsia with optic neuritis (ON) as the initial and only clinical feature of BNS.
Our case illustrated that BNS should be included in differential diagnosis of ON, especially of that
with atypical manifestation.
Journal of Multiple Sclerosis and Neuroimmunology 11(2):65-67, 2020