Journal of Multiple Sclerosis and Neuroimmunology 11(1):25-29, 2020
Multiple Cerebral and Spinal Astrocytoma Mimicking Tumefactive Demyelinating Disease
Dae Woong Bae, MD, Ko-Eun Choi, MDa , Jae Young An, MD
Department of Neurology, The Catholic University of Korea St. Vincent’s Hospital, Suwon, Korea Department of Neurology, The Catholic University of Korea Incheon St. Mary’s Hospital, Inhcheon, Koreaa
A 55-year-old male complained of gait disturbance and dysarthria for 2 weeks. Brain MRI
showed multiple ill-defined, scattered lesions, including a tumefactive enhancing lesion. Spinal
cord MRI showed a cord lesion at T2-3 without enhancement. Magnetic resonance spectroscopy
demonstrated a high choline/N-acetyl-aspartate ratio, suggesting malignancy. Stereotactic
biopsy revealed astrocytoma. Herein, we report an uncommon case of multiple gliomas involving
both the brain and spinal cord, mimicking central nervous system tumefactive demyelinating
diseases and metastatic diseases.
Journal of Multiple Sclerosis and Neuroimmunology 11(1):25-29, 2020
