A Case of Stiff-person Syndrome with Hodgkin Disease
Juhyeon Kim, Jea-Hong Park, Eun-Hyeok Choi, Ju-Hong Min, Byoung-Joon Kim
1Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 2Neuroscience Center, Samsung Medical Center, Seoul, Korea
Stiff-person syndrome (SPS) is characterised by progressive rigidity and muscle spasms affecting
the axial and limb muscles. Autoantibodies to the GABA-synthesizing enzyme glutamic acid decarboxylase,
present in about 60-85% of patients, have indicated an autoimmune pathogenesis.
Thus, other autoimmune diseases may occur or, rarely, neoplasms may occur together. We report a
case of a patient diagnosed with SPS at the age of 20 who was diagnosed with Hodgkin disease 4
years later.
Journal of Multiple Sclerosis 9(1):10-13, 2018
