Case Reports of Clinical Variability in Myelin Oligodendrocyte Glycoprotein (MOG ) Encephalom yelitis Patients
Sung Hyun Kim, MD, Dong Won Kwack, MD, Jeeyoung Oh, MD, PhD, Kyomin Choi, MD
Department of Neurology, Konkuk University Medical Center, Seoul, Korea
Most experts now consider myelin oligodendrocyte glycoprotein (MOG) antibody positive encepha-
lomyelitis as a disease entity immunopathogenetically distinct from multiple sclerosis and neuro-
myelitis optica spectrum disorder (NMOSD). MOG-encephalomyelitis patients usually present with
recurrent optic neuritis or limb paralysis due to myelitis, but also behavioral change, seizures, or en- cephalopathies are often the first manifestations in these patients. Herein, we report two cases of
MOG-antibody encephalomyelitis who presented with atypical symptoms that included aggressive
behavior, multiple cranial neuropathies, and seizures.
Journal of Multiple Sclerosis 10(2):32-35, 2019
keyword : Myelin-oligodendrocyte glycoprotein, Encephalomyelitis, Magnetic resonance imaging
