Reversible Pathological Laughing in a Multiple Sclerosis Patient
Ki Hun Son, MD, So-Young Lee, MD, Seong Hun Jeong, MD, Jin-Hyung Lee, MD, So-Young Huh, MD
Department of Neurology, Kosin University College of Medicine, Busan, Korea
Multiple sclerosis is a chronic neuroinflammatory disease of the brain and spinal cord. The clinical
manifestations are heterogeneous, but most cases show motor impairments, sensory or visual disturbances,
fatigue, pain and cognitive deficits. Pathological laughing and crying represents a paroxysm
of involuntary and uncontrollable laughter and crying that can be the presenting symptoms of a
neurologic disorder. Here we describe a patient with an inaugural diagnosed MS who exhibited reversible
pathological laughing.
Journal of Multiple Sclerosis 9(2):31-33, 2018