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Journal of Multiple Sclerosis 8(2):37-40, 2017
Primary Central Nervous System Lymphoma Mimicking Inflammatory Demyelinating Disease
Yoon-Jung Kang1, MD, Jin-Hong Shin2, MD, PhD, Jae-Won Hyun3, MD, PhD, Ho Jin Kim3, MD, PhD, Min-Jeong Song4, MD, PhD, Weon-Seo Park4, MD, PhD
1Department of Neurology, Pusan National University Hospital, Busan, 2Department of Neurology, Pusan National University Yangsan Hospital, Yangsan, 3Department of Neurology and 4Department of Pathology, Research Institute and Hospital of National Cancer C
Primary central nervous system lymphoma (PCNSL) is an uncommon form of lymphoma, mostly due to diffuse large B-cell lymphoma (DLBCL). At early stage, a PCNSL may mimic inflammatory lesions of multiple sclerosis (MS) or the other demyelinating diseases. Both PCNSL and MS may improve by high-dose steroid therapy, leading to the further confusion in differential diagnosis. We report a case of PCNSL by DLBCL, at first recognized to be MS, but later confirmed by brain biopsy.

Journal of Multiple Sclerosis
8(2):37-40, 2017
KEY WORDS : Diffuse large B-cell lymphoma, Demyelinating diseases, Diplopia